Definitely! Your journey to these historically rich cities in Uttar Pradesh will be profoundly absorbing.

Best Time to Visit:
The best time to visit would be from October to March when the climate is quite pleasant, making it suitable for sightseeing in Ayodhya, Varanasi, and Lucknow.

Route and Accessibility:
All these cities are well connected by road and rail. The nearest airport to Ayodhya and Varanasi is in Lucknow that serves as a convenient point of ingress for travelers.

Altitude and Acclimatization:
Unlike the Himalayan destinations, these cities do not require any specific acclimatization due to their low altitudes.

Accommodation and Booking:
From luxury to budget, you will find a variety of accommodation options in these cities. It is always a good idea to book your stay in advance, especially around popular events or festivals for the best experience.

Clothing and Essentials:
Being religious cities, carry modest and comfortable clothing. Don't forget to take an umbrella or a raincoat if you are visiting during the monsoon. Carry adequate woollen clothing if you are visiting during winters.

Health and Safety:
All the three cities have good medical facilities, but it's always advisable to carry your personal medical kit with basic medicines. Drink only bottled water and consume food from clean and reliable places to avoid any health problems.

Local Etiquette and Respect:
Ayodhya, Varanasi, and Lucknow have a deep cultural and religious significance. Dress modestly during religious visits. Respecting local traditions and customs is highly recommended. Be polite and courteous with the locals.