Absolutely! The four mentioned cities are historic and culturally rich cities in the southern state of Tamil Nadu, India. Here are some travel tips to guide you through your journey:

Best Time to Visit:
The ideal time to visit these cities in Tamil Nadu is between October to March, when the weather is pleasant and cool.

Route and Accessibility:
All the cities are well connected by road, rail and air.
Chennai is the primary entry point for most travelers, Chennai International Airport is available for international and domestic flights. With extensive rail and road networks, it's quite convenient to move from one city to another.

Altitude and Acclimatization:
These cities are all at sea level or slightly above, so altitude sickness isn't a concern. However, depending on the time you're visiting, the climate could be humid. So it's advisable to stay well-hydrated.

Accommodation and Booking:
There are range of accommodations available in all these cities suitable for every type of traveler. It's advisable to book in advance for the best deals and to ensure availability, particularly during festival seasons.

Clothing and Essentials:
As these cities can get hot and humid, carrying lightweight, breathable clothing is suggested. Always carry a hat, sunglasses and sunscreen for protection from the sun.

Health and Safety:
It's always good to keep a compact first aid kit handy. Also, check the safety standards of the places you'll be staying or visiting, especially if you're traveling solo or with family.

Local Etiquette and Respect:
Tamil Nadu has a rich culture, tradition and people here belong to different religious beliefs. So, dressing modestly especially at religious sites, respecting local customs, and getting permission before taking photographs of locals or religious ceremonies would be appreciated.